Ann Nyman - Associate Professor - SLU - Swedish University


Mikrobiologi – Åsa Melhus

The source of infection is unclear; suggestions include acquisition from animals or human-to-human transmission. The bacteria most commonly responsible for Lemierre syndrome is Fusobacterium necrophorum (F. necrophorum). This bacteria is normally present in healthy people in various parts of the body (including the throat, digestive tract, and female genitals). The bacteria may cause invasive disease by releasing toxins into surrounding tissue.

F necrophorum

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1 x 106 CFU/mL. –. –. Haemophilus parainfluenzae. 1 x 105 CFU/mL.


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F. necrophorumin kaksi merkittävintä alalajia ovat F. necrophorum subsp. necrophorum, joka on eläinten patogeeni ja F. necrophorum subsp.

F necrophorum

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Fusobacterium necrophorum is the most common species in infections of animals (Langworth, 1977).

necrophorum) som är en obligat, anaerob bakterie. Många andra bakterier. Oral nekrobacillos som orsakas av bakterien Fusobacterium necrophorum, är inte så vanlig i Sverige idag, men vissa besättningar kan få stora problem. Misstanke om infektion med Fusobacterium necrophorum eller Arcanobacterium haemolyticum. Metoden lämpar sig också för att påvisa F. necrophorum och A. Fusobacterium PCR. Fusobacterium PCR. Klinisk mikrobiologi; Externt laboratorium. Fusobacterium necrophorum PCR. Laboratorium.
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F necrophorum

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Especially, most cases of frank jaundice or hyperbilirubinemia due to F. necrophorum infection had a thrombus in the internal jugular vein, which progressed to Lemierre’s syndrome . Fusobacterium necrophorum findings in Denmark and estimation of the incidence of F. necrophorum bacteraemia was described using data from the nationwide Danish microbiology database (MiBa). All microbiological reports on any Fusobacterium species in Denmark were extracted for a period of 5 years from 2010 to 2014 from MiBa and from the local department of clinical microbiology. F. necrophorum occurs naturally in the animal's environment, especially in wet, muddy, or unsanitary conditions, such as an unclean stall.
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Lemierres syndrom – Wikipedia

Characteristics. F.necrophorum is pleimorphic and is either long and filamentous or a short cocci. Fusobacterium necrophorum is a gram-negative anaerobic bacillus that can cause serious systemic infections typically in previously healthy young adults. Lemierre's syndrome, also known as post-anginal sepsis or necrobacillosis, is the infection most usually associated with F. necrophorum.

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It produces grey, round and shiny colonies. There are three biotypes, biotype A has 2005-12-31 2020-03-04 F. necrophorum is also associated strongly with peritonsillar abscess and has recently been connected with tonsillitis [ 2 - 4 ]. F. necrophorum is traditionally described as forming part of the normal flora of the oropharynx, gastrointestinal tract and genitourinary tract of humans, but convincing evidence is lacking [ … 2017-04-01 F. necrophorum is a gram-negative anaerobic bacterium that is difficult to grow on routine media from throat swabs. Blood cultures grow the organism, but identification is slow. “F. necrophorum, which only has been recognized as a potential cause of pharyngitis in adolescents and young adults in the past five years, may cause up to 10 percent of sore throat in those 15-24 years of age,” said Robert Centor, M.D., professor of internal medicine, associate dean of medicine at UAB and the paper’s lead author.